Molecular and cellular biology of the allergic response

Cover of: Molecular and cellular biology of the allergic response |

Published by M. Dekker in New York .

Written in English

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  • Allergy -- Pathophysiology.,
  • Molecular immunology.,
  • Cellular immunity.,
  • Immunity, Cellular.,
  • Hypersensitivity -- immunology.,
  • IgE -- immunology.,
  • T-Lymphocytes -- immunology.,
  • Antigens -- immunology.

Edition Notes

Includes bibliographical references and index.

Book details

Statementedited by Arnold I. Levinson, Yvonne Paterson.
SeriesClinical allergy and immunology ;, 3
ContributionsLevinson, Arnold I., 1944-, Paterson, Yvonne, 1941-
LC ClassificationsQR188 .M64 1994
The Physical Object
Paginationxi, 453 p. :
Number of Pages453
ID Numbers
Open LibraryOL1080930M
ISBN 100824788761
LC Control Number94004449

Download Molecular and cellular biology of the allergic response

Providing a thorough overview of the fundamental elements of the human allergic immune response, this up-to-date reference focuses on the unique molecular and cellular features of the IgE-mediated immune response-relating these features to current knowledge of the immune response to protein antigens.

ISBN: OCLC Number: Description: xi, pages: illustrations ; 23 cm. Contents: Basic features of the immune response --Molecular genetics of immunoglobulin genes and the generation of antibody diversity / Mark Ballow, Frederick M.

Schaffer --Molecular mechanisms of transmembrane signaling in B-cell differentiation and activation / Stephen Desiderio, Susan. Molecular and cellular biology of the allergic response. Publication date Topics Allergy -- Pathophysiology, Molecular immunology, Cellular immunity, Immunity, Cellular, Hypersensitivity -- immunology, IgE -- immunology, T-Lymphocytes -- immunology, Antigens -- immunology Borrow this book to access EPUB and PDF files.

IN COLLECTIONS. Cellular and Molecular Immunology. This lecture note explains cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically.

Cellular and Molecular Immunology by NPTEL. This book covers the following topics: Properties of Immune system, Innate immune system, Adaptive immune system, Antibodies and Antigens, Development of Lymphocytes, Activation of Lymphocytes, B cell activation and antibody production, Immune memory response, Cytokines, Mechanism of cell mediated immune response, Mechanism of.

Allergic reactions are triggered when allergens cross-link preformed IgE bound to the high-affinity receptor FcεRI on mast cells. Mast cells line the body surfaces and serve to alert the immune system to local infection.

Once activated, they induce inflammatory reactions by secreting chemical mediators stored in preformed granules, and by synthesizing leukotrienes and cytokines after Cited by: 5.

Written by over 20 internationally renowned experts, Molecular and Cellular Biology of the Allergic Response describes T- and B-cell development and activation examines important genetic and structural features of the major histocompatibility complex details antigen processing and presentation explores the molecular and cellular biology of mast.

Molecular and Cellular Biology of the Allergic Response (Clinical Allergy and Immunology). CRC Press, Find helpful customer reviews and review ratings for Cellular and Molecular Biology at Read honest and unbiased product reviews from our users/5(13).

Cellular and Molecular Immunology E-Book E-bok,Engelska, ISBN Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Molecular and Cellular Biology of the Allergic Response av Arnold I.

(EDT). 3. Regulatory T Cells and IL Although TGF-β is the major known driver of iTreg differentiation, IL has been shown to be another key player that has been vastly described in protection from allergic diseases [].Studies with bee venom-specific immunotherapy have shown that tolerance to the allergen can be induced in a process that is IL mediated [].Cited by: 7.

New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem. Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune.

A Th1 response is characteristic of certain autoimmune disorders (eg, type 1 diabetes, multiple sclerosis), and a Th2 response promotes IgE production and development of allergic disorders, as well as helps B cells produce autoantibodies in some autoimmune disorders (eg, Graves disease, myasthenia gravis).

Using a combination of cellular and molecular attacks, the innate immune system identifies the nature of a pathogen and responds with inflammation, phagocytosis, cytokine release, destruction by NK cells, and/or a complement system. When innate mechanisms are insufficient to clear an infection, the adaptive immune response is informed and Author: Charles Molnar, Jane Gair, Molnar, Charles, Gair, Jane.

Molecular Biology of Allergens: Structure and Immune Recognition frequently hav e oral symptoms (itching at the back of the throat) upon eating apples and other soft fruits.

New Insights to Neuroimmune Biology investigates the mechanisms that and functions of the Neuroimmune Regulatory Supersystem.

Covering molecular regulation of cytokines in brain astrocytes, immunoregulation by the sympathetic nervous system, circadian regulation of immune reactions, antigen recognition by the CNS, the modulation of the immune response by head injury, Pages: C-reactive protein and mannose-binding lectin fix complement and act as opsonins.

Alpha-1 acid glycoprotein is a transport protein. Serum amyloid P component activates complement. Elevated C-reactive protein levels are a nonspecific indicator of infection or inflammation. Fibrinogen levels also. Clinical and Molecular Allergy is an open access, peer-reviewed journal that covers all aspects of allergy research with a special focus on molecular allergy and clinical applications of molecular al and Molecular Allergy is the official journal of the Italian Society of Allergology, Asthma and Clinical Immunology.

This international journal appeals to allergists. The molecular and cellular mechanisms mediating the allergic inflammatory cascade involve multiple mediators, cell types, and pathways.

Of particular interest are the pathways regulated by the T H 2 lymphocyte, which result in release of IL-4 (important to IgE synthesis) and IL-5 (important to eosinophil proliferation). IL-4 regulates differentiation of naïve T H 0 cells to develop a T H 2 Cited by: Cellular and Molecular Biology of Filamentous Fungi begins with an historical perspective, cell morphology and taxonomy, and then moves on to such topics as cell growth, development, metabolism, and pathogenesis.

The book covers model organisms in detail as well as a broad variety of dimorphic and “obligate” filamentous fungal species. Figure shows an example of an allergic response to ragweed pollen. The effects of an allergic reaction range from mild symptoms like sneezing and itchy, watery eyes to more severe or even life-threatening reactions involving intensely itchy welts or hives, airway contraction with severe respiratory distress, and plummeting blood pressure.

of very important cell biology to be learned by looking at cells of the immune system, but it also provides a lot more. It provides you with the opportunity to actually understand how events that occur at the molecular level and at the cellular level.

Cellular and Molecular Immunology book. Read 11 reviews from the world's largest community for readers. This highly acclaimed text is now more up to date 4/5.

Cells, an international, peer-reviewed Open Access journal. Dear Colleagues, Welcome to this Special Issue of Cells on “Molecular and Cellular Basis for Allergies and Asthma". Allergies and Asthma are chronic health conditions that range in frequency and severity from mild to life-threatening symptoms, which vary from person to person.

Cellular, molecular, and clinical aspects of allergic disorders. New York: Plenum Medical Book Co., © (DLC) (OCoLC) Material Type: Document, Internet resource: Document Type: Internet Resource, Computer File: All Authors / Contributors: Sudhir Gupta; Robert A Good.

One of the most intensively studied animal models of autoimmunity is insulin-dependent diabetes mellitus (IDDM) in the nonobese diabetic (NOD) mouse. This chapter considers how molecular mimicry, when viewed in the broader context of degeneracy of T-cell recognition specificity, provides a rationale for the existence of frequent : Anthony Quinn, Eli E.

Sercarz. Molecular pathology of allergic disease Article Literature Review in Journal of Allergy and Clinical Immunology (2 Pt 1) March with 23 Reads How we measure 'reads'. Allergies. The immune reaction that results from immediate hypersensitivities in which an antibody-mediated immune response occurs within minutes of exposure to a harmless antigen is called an the United States, 20 percent of the population exhibits symptoms of allergy or asthma, whereas 55 percent test positive against one or more allergens.

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The immune system comprises both innate and adaptive immune responses. Innate immunity occurs naturally because of genetic factors or physiology; it is not induced by infection or vaccination but works to reduce the workload for the adaptive immune response. Both the innate and adaptive levels of the immune response involve secreted proteins, receptor-mediated signaling, and intricate cell-to.

Allergic diseases affect approximately one third of the general population. This class of disease, characterized by elevated serum IgE levels and hypersensitivity to normally innocuous antigen, can manifest in practically any mucosal tissue or as a systemic response.

A few examples of serious allergic diseases include asthma, dermatitis, bee sting allergy, food allergy, conjunctivitis, and. International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. This most current release in this highly cited series focuses on such timely topics as novel treatments in immunotherapy in breast cancer, chemokine receptor signaling and the hallmarks of cancer, tumor-targeting antibodies, and a section on mitochondrion and whether they are.

CD1-reactive T cells with conserved (NK T cells) or diverse T cell receptors possess cytokine secretion and other effector mechanisms that influence many aspects of immune response. There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol.

Unit 3 Signatures of Life Applications of molecular biology in medicine including the design of drugs and in medical diagnosis. disorders of the human immune response including the allergic response and autoimmune diseases ; acquired immunity through natural and passive strategies, including the nature and production of vaccines and.

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natural killer cell A cell type that provides an innate immune response by attacking cancer cells and infected body cells, especially those harboring viruses. On-Line Biology Book: GLOSSARY M. macroevolution The combination of events associated with the origin, diversification, extinction, and interactions of organisms which produced the species that currently inhabit the Earth.

Large scale evolutionary change such as the evolution of new species (or even higher taxa) and extinction of species. This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of genetics, Glossary of ecology, Glossary of speciation, Glossary of botany, and Glossary of.

The Laboratory of Immune System Biology (LISB) is focused on the basic genetics, molecular biology, and cell biology of the immune system, as well as on human disease informed by these more basic studies. How dysregulation of the immune system results in immunodeficiencies, autoimmunity, inflammation, allergy, chronic infections, and lymphoproliferative diseases and what strategies might.

A survey of mast cell biology offers insight into its history and the implications for adaptive immunity. The protocols follow the successful Methods in Molecular Biology series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents.

Allergic asthma is a common chronic respiratory disease involving the T-helper cell type 2 (Th2) immune response. Th2-type cytokines released by cluster of differentiation 4-positive (CD4 +) Th2 cells are the main inducers of asthma (1–4).Repeated exposure to allergens stimulates the release of IL-4, IL-5, and IL, which activate IgE and eosinophilic by: 6.She worked as Research Associate at CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad from She has experience in the field of proteomics.

She has 12 research publications in international peer-reviewed journals and one book chapter.The study of immune regulation and tolerance has been traditionally associated with self/nonself-discrimination.

However, the finding that dominant tolerance, a model that puts in evidence the active role of regulatory T cells, can develop to nonself-antigens suggests that the imposition of tolerance can be context dependent.

This paper reviews the emerging field of acquired immune tolerance Cited by: 7.

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